Endocrine Abstracts

Background: Primary hyperparathyroidism (PHPT) is often only mildly sympthomatic1. Nevertheless, some patients are diagnosed late and severe complications such as osteitis fibrosa cystica can develop.Case Presentation: A 32 years old female was hospitalized due to pain in the left femoral region after falling from standing height. Radiological investigations revealed left femoral pathologic fracture and bone malignancy was suspected. Further r...

According to the hypothesis, the capillary albumin leakage parallels the degree of microalbuminuria, probably reflecting a generalized basement membrane abnormality, and relates with microvascular disfunction. The AIM of our study was to estimate postocclusive reactive hyperaemic response in patients with microalbuminuria. MATERIALS: Patients with microalbuminuria were divided into two groups: 18 patients with diabetic nephropathy (N) and 18 non-diabetic patients with glomerul...

High dose glucocorticoids reduce hepatic and peripheral insulin sensitivity and insulin secretion. However, the metabolic consequences of typical therapeutic glucocorticoid doses (e.g. prednisolone <10 mg/day) are poorly characterised. The aim was to determine the acute effect of low dose prednisolone on carbohydrate metabolism and then assess whether subjects taking chronic prednisolone had increased adiposity that amplified carbohydrate metabolism perturbations.<p cl...